Endocrine Abstracts

Aim: Hyperinsulinaemia is frequent finding in patients with hyperprolactinemia and has associations with thyroid volume. In this study, we evaluated the association between thrombotic markers, insulin resistance, CIMT, and thyroid volume in female patients with prolactinoma.Material and methods: 38 women with prolactinoma and 24 healthy women were included to the study. We evaluated anthropometric, biochemical, hematologic and hormonal parameters as well...

Background: In Belgium, a land with borderline iodine intake, the prevalence of goiter is 6 to 40%. This raises the question of an economically affordable treatment with few side effects. In euthyroid goiters, the effect of radioiodine on volume reduction is debated. Most data were described last century and do not take into account recent thyroid hormone measurements, newer ultrasonography techniques and changes in iodine supplementation. Doses administered in the past and el...

Background: Radioiodine(RAI) has been used to treat hyperthyroidism for more than seven decades. Effects of RAI treatment on thyroid function tests(TFT), risk of hypothyroidism, gland and autonomous nodule volumes and on ultrasonographic features in toxic adenoma (TA) and toxic multinodular goitre TMNG patients, have been previously studied by ourselves and other. However, studies evaluating ultrasonographic changes in thyroid and toxic nodule volumes usually have a follow-up ...

Background: Larger thyroid volume and nodular thyroid disease were found to be associated with insulin resistance (IR) in patients with type 2 diabetes (T2DM). Similar analyses is lacking in T1DM.Aims: To check the association between thyroid volume and IR using estimated glucose disposal rate (eGDR) in patients T1DM.Materials and methods: We included 99 consecutive patients with T1DM aged 29 (mean, S.D.=6) with diab...

Introduction: Aim: it is known that environmental factors are involved in the development of goiter. A high number of goitrous patients was identified among patients attending the general medicine outpatients’ in a mountainous region in Albania. We examined possible associations of thyroid enlargement with nutritional factors.Methods: One hundred and twelve consecutive patients (mean age 52.8±12.1, 104 female) attending the outpatients of the G...

Actuality: Currently, there is no doubt about the negative effect of diabetes mellitus (DM) on the state of the central nervous system. One of the pathological manifestations are anatomical changes in the brain, which in turn can lead to the development of functional disorders and cognitive decline. Conducting imaging research methods allows us to assess the presence or absence of brain atrophy at an early stage.The aim: To identify the relationship betw...

Aim: To investigate the volumetric changes in cortical and subcortical deep gray matter (GM) structures and cognitive alterations in patients with mild autonomous cortisol secretion (MACS). We also sought to assess whether the anticipated changes in brain volume and cognitive functions of the patients with MACS differ from the changes in patients with overt Cushing’s Syndrome (CS). Methods: In this cross-sectional study, volumes of the cortex, hippo...

Aim: Most diabetic patients suffer from vascular thrombotic complications. Alterations in platelet size are associated with atherosclerotic complications in patients with diabetes. The aim of study is to determine the relationship between mean platelet volume (MPV) and microvascular complications in type 2 diabetic patients.Materials and methods: Seventy-nine type 2 diabetic patients (mean age 51.0±10.8 years and BMI 31.0±5.5 kg/m2),...

The aim of our study was to investigate de relationship between anthropometric and body composition parameters and thyroid function (measured with TSH and free T4), as well as thyroid volume, in patients with obesity.Methods: This is a cross-sectional study including patients with obesity consecutively referred to our tertiary endocrine center for diverse pathologies. TSH and free T4 was measured in all patients and thyroid ultrasound was performed by an...

Background and aim: The normal range of thyroid functions during pregnancy differs between ethnic groups. The aim of this work was to assess the thyroid functions in normal pregnant Egyptian females in order to establish a population-specific reference range. Thyroid peroxidase antibodies (TPO Abs) and thyroid volume were also assessed.Methods: The study included 150 normal pregnant Egyptian females (with no history suggestive of thyroid...